A less invasive approach

Intrauterine insemination (IUI)

Intrauterine insemination is often the first treatment option considered when fertility treatment becomes necessary. It is a precise medical procedure, performed under rigorous conditions, and is suitable for many clinical situations.

The principle is simple: a sperm sample, prepared and concentrated in the laboratory, is placed directly into the uterus at the time of ovulation. By reducing the distance sperm must travel to reach the egg, IUI increases the chances of natural fertilization without taking this process outside the body.

Who is IUI for?

Intrauterine insemination may be recommended in several different situations.
For heterosexual couples, IUI may be indicated when the fallopian tubes are open and ovarian reserve is adequate, in cases of mild to moderate male infertility (reduced sperm concentration or motility, without severe impairment), for ovulatory disorders that respond well to stimulation, or in cases of unexplained infertility following a complete fertility assessment.
For single women or female couples, IUI with donor sperm is a direct, medically supervised option to begin a family-building journey.

How does intrauterine insemination work?

An IUI cycle lasts approximately two to three weeks. Here are the steps, in order.

1.

Ovarian stimulation

2.

Cycle monitoring

3.

Sperm preparation

4.

Insemination

5.

Rest and follow-up

Partner sperm or donor sperm

IUI can be performed using sperm from a partner or sperm from an anonymous donor or known donor. In both cases, the sperm sample is prepared in the laboratory before insemination. Your physician will guide you in choosing the option that is best suited to your situation.

Our partner distributors Donor sperm used at Miacleo comes from approved distributors that are inspected and comply with Health Canada standards: Can-Am Cryoservices, Canada Cryobank, Xytex Canada, and Origin Sperm Bank. These distributors perform rigorous donor screening before samples are made available. We recommend that you consult their websites directly to view the donors available in Canada.

IUI and IVF: understanding the difference

How do you know which one is right for you? IUI and IVF are used in different clinical situations. IUI works with the body: it optimizes the conditions for natural fertilization by placing sperm where they have the greatest chance of meeting the egg. IVF, on the other hand, takes fertilization outside the body and performs it entirely in the laboratory, allowing for greater control and treatment of more complex situations. In general, IUI is considered first when anatomical and biological conditions allow for it. If several IUI cycles do not lead to the expected results, or if the initial assessment reveals a situation requiring a more advanced approach, IVF may then be discussed. Your physician will explain their recommendation and the reasons behind it with transparency.

Q: How many IUI cycles are usually attempted before moving to IVF?

A: In general, three to six cycles may be recommended before considering another approach, depending on age, diagnosis, and response to treatment. This decision is made individually, in discussion with you. There is no universal rule, only what is right for your specific situation.

Q: Is IUI painful?

A: The vast majority of patients describe the procedure as mildly uncomfortable, but not painful. Mild cramping may occur during or after the insemination, similar to menstrual cramps. These usually disappear within a few hours.

Q: Does IUI increase the risk of multiple pregnancy?

A: When ovarian stimulation is used, the risk of twin pregnancy is slightly increased. Your physician closely monitors the number of developing follicles and adjusts the protocol if needed to help reduce this risk. Patient and pregnancy safety always guide treatment decisions.

Q: Can I work on the day of the insemination?

A: Yes, in most cases. The procedure takes little time and does not require sedation. A short period of rest after the procedure is recommended, but you can generally return to your normal activities later the same day.

Q: Does RAMQ cover IUI?

A: Some medical indications may qualify for partial or full coverage depending on your situation. Our team can help you verify your eligibility. Please contact us before your first consultation.

Ready to take the first step?